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Published on:
August 27, 2026

Advanced Nerve Blocks: Targeted Pain Relief When Other Treatments Aren’t Enough

Katlin McFerrin
BSN, RN
Medical Reviewer

When chronic pain becomes overwhelming — burning, stabbing, radiating, or deep and constant — it often comes from nerves that are inflamed, compressed, or overly sensitive. Medications may help temporarily, but they rarely treat the source. Physical therapy can improve strength and mobility, but it cannot always calm irritated nerves.

That’s where advanced nerve blocks come in.

At Genesis Wellness and Pain, nerve blocks are one of the most powerful tools we use to diagnose and treat nerve‑based pain. These procedures deliver medication directly to the affected nerve, interrupting pain signals and reducing inflammation with remarkable precision.

Using ultrasound or fluoroscopy, we can see the nerves and the spaces where they run — allowing us to place medication exactly where it’s needed while minimizing risk.

What Are Nerve Blocks?

A nerve block is a targeted injection that delivers medication around a specific nerve or group of nerves.

The goal is simple: Stop the nerve from sending pain signals.

Depending on the condition, nerve blocks may include:

  • Local anesthetic (for immediate relief)
  • Steroid medication (to reduce inflammation)
  • A combination of both

Because nerve blocks are image‑guided, they are extremely precise — making them ideal for patients whose pain has not responded to conservative treatments.

Why Nerve Blocks Work When Other Treatments Don’t

Nerve blocks are uniquely effective because they:

1. Target the Exact Source of Pain

Instead of treating the whole body, nerve blocks treat the specific nerve causing the problem.

2. Reduce Inflammation Quickly

Medication is placed directly around the irritated nerve root or ganglion.

3. Calm Overactive Nerves

Many chronic pain conditions involve nerves that are “stuck” in a hypersensitive state.

4. Improve Mobility and Function

Patients often experience immediate or rapid relief.

5. Provide Diagnostic Clarity

If a nerve block relieves pain, it confirms the exact nerve responsible — guiding future treatment.

Advanced Nerve Blocks Offered at Genesis Wellness and Pain

Our clinic offers a wide range of specialized nerve blocks — many of which are not available at typical pain clinics. Each one treats a specific type of pain or nerve pathway. Below is a clear, patient‑friendly explanation of each.

Celiac Plexus Block

Used for severe abdominal pain, including pain from chronic pancreatitis or upper abdominal nerve irritation.

Ganglion Impar Block

Targets pelvic, rectal, and perineal pain — especially helpful for chronic pelvic pain syndromes.

Intercostal Nerve Block

Treats rib pain, post‑surgical chest pain, and nerve irritation between the ribs.

Lumbar Sympathetic Block

Used for Complex Regional Pain Syndrome (CRPS), burning leg pain, and nerve hypersensitivity in the lower body.

Pudendal Nerve Block

Treats pelvic floor pain, vaginal or rectal pain, and nerve‑related discomfort in the perineal region.

Sphenopalatine Ganglion (SPG) Block

Highly effective for migraines, facial pain, and trigeminal autonomic cephalalgias.

Stellate Ganglion Block

Used for CRPS of the upper extremities, facial pain, and certain nerve‑related head and neck conditions.

Suprascapular Nerve Block

Provides relief for shoulder pain, rotator cuff injuries, and frozen shoulder.

Trigeminal Nerve Block

Targets trigeminal neuralgia and severe facial pain — often life‑changing for patients with electric, stabbing facial symptoms.

What to Expect During a Nerve Block Procedure

Before the Procedure

  • A full evaluation
  • Review of imaging
  • Discussion of symptoms and goals

During the Procedure

  • The skin is cleaned and numbed
  • Ultrasound or fluoroscopy guides precise needle placement
  • Medication is injected around the targeted nerve
  • Most procedures take less than 20 minutes

After the Procedure

  • Patients are monitored briefly
  • Mild soreness is normal
  • Relief may be immediate or develop over several days
  • Activity restrictions are minimal

Who Benefits Most From Advanced Nerve Blocks?

Nerve blocks may be recommended for patients with:

  • Chronic nerve pain
  • CRPS
  • Facial pain or trigeminal neuralgia
  • Pelvic or rectal pain
  • Shoulder pain
  • Rib pain
  • Migraines
  • Post‑surgical nerve irritation
  • Pain that radiates or burns
  • Pain that has not responded to medications or therapy

These procedures are especially effective when nerve inflammation or hypersensitivity is the primary driver of pain.

Precision That Heals

Advanced nerve blocks offer a powerful, minimally invasive way to calm irritated nerves and restore comfort. At Genesis Wellness and Pain, our team uses image‑guided nerve blocks as part of a comprehensive, personalized plan designed to help patients move better, feel better, and live with less pain — even when other treatments have failed.